| COMPOSITION |
Tablet : Each tablet contains
Dried Aluminium Hydroxide Gel BP 250 mg
(Al2O3 47%, minimum)
Magnesium Hydroxide BP 400 mg
|
| PHARMACOLOGY |
D-Antacid tablet and suspension are well-balanced combination of essential non-systemic antacids which excel in efficacy and palatability. These are
dependable antacid preparations without acid rebound, constipating or
cathertic effects. Both the preparations provide symptomatic relief of
hyperacidity associated with heartburn, acid ingestion or sour stomach.
Aluminium hydroxide gel, a slow acting antacid and an adsorbent with
prolonged effect, has high neutralizing power. Magnesium Hydroxide
possesses a slow but sustained acid neutralizing property. Antacids of both
tablet and suspension possess adsorbent property. They form a protecting
coating over the ulcer surface facilitating its healing; thus protecting the
sensitive mucosa of stomach and duodenum from further irritation.
|
| INDICATIONS |
Hyperacidity , peptic ulcer, gastritis, heartburn, sour stomach & dyspepsia. |
| DOSAGE AND ADMINISTRATION |
Tablet: Two tablets 1-3 hours after meal and at bed time or as directed by
the physician.
|
| CONTRAINDICATION AND PRECAUTION |
Antacid is contraindicated in hypophosphataemia. It is also contraindicated
in alkalosis and hypermagnesaemia where abdominal distention may be
due to partial or complete intestinal obstruction.
Aluminium Hydroxide & Magnesium Hydroxide
|
| ALIMENTARY PREPARATIONS |
|
Antacids reduce the absorption of tetracycline when given concomitantly.
These should not be used concomitantly.
|
| SIDE EFFECTS |
|
Long term use of any antacid results in alkaluria, which may predispose to
nephrolithiasis by forming precipitation of calcium phosphate.
|
| DRUG INTERACTIONS |
|
Antacids reduce absorption of different groups of drugs as shown in the
following tableTable: Name of the drugs, the absorption of which is inhibited by antacid
Therapeutic class Example of drugs
Antibacterials Azithromycin, cefpodoxime, ciprofloxacin,
isoniazid, rifampicin, norfloxacin, ofloxacin,
pivampicillin and most tetracyclines.
Antiepileptics Gabapentin and phenytoin
Antifungals Itraconazole and ketoconazole.
Antimalarials Chloroquine and hydroxychloroquine.
Antipsychotics Phenothiazines..
|
| USE IN PREGNANCY
|
|
It is advised to avoid antacid preparations in the first trimester of pregnancy.
|
| STORAGE CONDITION |
|
Store in cool and dry place, out of reach of children.
|
| HOW SUPPLIED |
|
D-Antacid tablet : Box containing 10 x 10 tablets in blister pack.
|
