| DESCRIPTION |
Amynophylline BP each stable mixture or combination of theophylline and ethylenediamine. Ethylenediamine confers greater solubility in water .
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| COMPOSITION |
D- Amynophylline Tablet: Each tablet contains Amynophylline 100mg.
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| INDICATIONS |
It is indicated for the treatment and prophylaxis of bronchospasm associated with asthma, emphysema and chronic bronchitis. Also indicated in adults for the treatment of cardiac asthma and left ventricular or congestive cardiac failure. |
| DOSAGE AND ADMINISTRATION |
By mouth : Adult , initially 100-200mg 2-3 times daily for one week, then maintenance 200-600mg twice daily. Child under 1 year not recommended; over 1 year 12mg/kg body weight twice daily.
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| CONTRAINDICATION |
Amynophylline should not be administered to patients with active peptic ulcer, since it may increase the volume and acidity of gastric secretion.
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| SIDE EFFECTS |
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The most common adverse effects are gastric irritation, nausea, vomiting, epigastric pain and tremor. These are usually early symptoms; however, with high doses ventricular arrhythmias or seizures may be the first signs to appear.
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| USE IN PREGNANCY & LACTATION
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Amynophylline crosses the placental barrier and also passes freely into breast milk, where concentrations are similar to plasma levels .safe use in pregnancy has not been established.
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| PRECAUTIONS
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Amynophylline should be given with caution to patients with peptic ulceration, hyperthyroidism, hypertension, cardiac arrhythmias or other cardiovascular diseases, or epilepsy, as these conditions may be exacerbated.
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| STORAGE |
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Store in a cool and dry place, protected from light.
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| HOW SUPPLIED |
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D-Amynophylline Tablet: Each carton contains 10x10 tablets in blister pack.
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