| DESCRIPTION |
D-Paracetamol is a preparation of paracetamol. Paracetamol has analgesic and antipyretic properties. D-Paracetamol produces analgesia by elevating the pain threshold level and antipyresis through action on the hypothalamic heat-regulating center.
|
| INDICATIONS |
D-Paracetamol is indicated in relieving fever and mild to moderate pain such as headache, toothache, neuralgia, rheumatic disorders, dysmenorrhoea, earache, general aches and pains, cold, influenza and pain due to trauma. |
| DOSAGE AND ADMINISTRATION |
Adults : 0.51 g every 46 hours to a maximum of 4 g daily
Children:
Under 3 months : On doctor's advice only, 10 mg/kg (if jaundiced 5 mg/kg)
3 months1 year : 60120 mg
15 years : 120250 mg
612 years : 250500 mg
Note: These doses may be repeated every 46 hours when necessary (maximum of 4 doses in 24 hours)
|
| OVERDOSE |
Overdose with paracetamol may result in severe liver damage and sometimes-acute renal tubular necrosis. Therefore, if overdose occurs it should be treated promptly by gastric lavage followed by IV N-acetylcysteine or oral methionine. Other supportive treatment should be considered according to clinical conditions of the patients.
|
| USE IN PREGNANCY AND LACTATION |
|
There is epidemiological evidence of safety with paracetamol. Paracetamol excreted in breast milk, which is clinically insignificant in quantity.
|
| CONTRAINDICATIONS |
|
D-Paracetamol is contraindicated for patients with known hypersensitivity to paracetamol.
|
| PRECAUTIONS |
|
Caution should be taken in patients with hepatic and renal impairment and in alcohol dependence.
|
| SIDE-EFFECTS |
|
Side-effects are rare, but rashes, blood disorders and acute pancreatitis are reported after prolonged use.
|
| PHARMACEUTICAL PRECAUTION |
|
Store in a cool and dry place, away from light. Keep out of reach of children
|
| PACKAGING |
|
D-Paracetamol tablet : Box contatining 25 strips of 20 tablets each. Each tablet contains paracetamol BP 500 mg.
D-Paracetamol suspension : Bottle containing 60/100 ml suspension. Each 5 ml contains paracetamol BP 120 mg.
|