| Composition |
D-Mebendazole100 mg Tablet : Each tablet contains Mebendazole USP 100 mg.
D-Mebendazole30 ml Suspension: Each 5 ml contains Mebendazole USP 100 mg.
|
| Mode of action |
Mebendazole inhibits the formation of the worms' microtubules and causes the worms' glucose depletion. |
| Indications |
Mebendazole is indicated for the treatment of Enterobius vermicularis (pinworm),Trichuris trichiura (whipworm), Ascaris lumbricoides (roundworm), Ancylostoma duodenale (hookworm), Necator americanus (American hookworm) in single or mixed infections.
|
| Dosage & administration |
Dose Duration
Pinworm
(Enterobius vermicularis) 1 tablet Once
Whipworm
(Trichuris trichiura) 1 tablet
Roundworm
(Ascaris lumbricoides) 1 tablet
Hookworm
(Ancylostoma duodenale) 1 tablet
or 1 spoonful of suspension in the morning & evening for 3 consecutive days.
|
| Side Effects |
|
Gastrointestinal : Transient symptoms of abdominal pain and diarrhea in case
of massive infection and expulsion of worms. Hypersensitivity: Rash, urticaria and angioedema have been observed on rare occasions. Central Nervous System: Very rare cases of convulsions have been reported. Hematologic: Neutropenia and agranulocytosis.
|
| Use in pregnancy & lactation |
|
Mebendazole is not recommended in pregnant women. Nursing mother: It is not known whether Mebendazole is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Mebendazole is administered to a nursing woman. Pediatric use: The drug has not been extensively studied in children under two years; therefore, in the treatment of children under two years the relative benefit/risk should be considered.
|
| Precautions |
|
General: Periodic assessment of organ system functions, including hematopoietic and hepatic, is advisable during prolonged therapy. Information for Patients: Patients should be informed of the potential risk to the fetus in women taking Mebendazole during pregnancy, especially during the first trimester. Patients should also be informed that cleanliness is important to prevent reinfection & transmission of the infection.
|
| Contraindications |
|
Mebendazole is contraindicated in persons who have shown hypersensitivity to the drug.
|
| Presentation |
|
D-Mebendazole100 mg Tablet : Each box contains 6x10,s tablets in blister pack.
D-MebendazoleSuspension : Each bottle contains 30 ml suspension
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