After entering into bacterial cell Doxycycline binds with 30s ribosomal sub-unit of bacteria, so bacterial protein synthesis is inhibited. As protein synthesis is inhibited so bacterial growth is retarded and finally the bacteria are died.
Doxycycline- The dependable antiobiotic for treatment of STD's
Gonococcal infections 97.7% cure rate
Non- Gonococcal urethritis 94% cure rate
Pelvic inflammatory diseases 95%
Acute urethal syndrom 88%
In a double blind randomized study showed that a single oral dose of Doxycycline 400 mg, given 10 to 12 hours before induced abortion, reduced the infection rate from 6.2 to 2.1%.
(Ref : Obstetric and Gynocology, Vol. 70, No. 5, Nov. 1987)
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