D-Amoxy(amoxicillin) is a broad spectrum penicillin effective against a wide range of Gram-positive and Gram-negative pathogens. Peak plasma concentrations of amoxicillin have been observed 1 to 2 hours after an oral dose. Amoxicillin is widely distributed at varying concentration in body tissues and fluids.

In the treatment of following infections caused by sensitive pathogens

Otitis media, sinusitis, tonsillitis, pharyngitis, laryngitis, pneumonia, acute and chronic bronchitis, lung abscess, empyema, bronchiectasis.

Typhoid and paratyphoid.

Pyelonephritis, cystitis, and urethritis.

Gonorrhoea.

Cellulitis, carbuncles, furunculosis, infected wounds, abscess.

Septicaemia, septic abortion, puerperal sepsis, endocarditis, osteomyelitis, intra-abdominal sepsis.

Adult: 250 mg three times daily, increasing upto 500 mg three times daily for severe infections.
Children: Upto 10 years of age, 125 mg to 250 mg three times daily. Sever or recurrent purulent respiratory infection, 3 gm every 12 hours.
Short-coursetherapy: Dental abscess, 3 gm repeated after 8 hours. Urinary tract infections, 3 gm repeated after 10-12 hours. Gonorrhoea, single dose of 2-3 gm with probenecid 1 gm. Otitis media,
Child: 3-10 years, 750 mg twice daily for 2 days.
In renal impairment the excretion of the antibiotic will be delayed and, depending on the degree of impairment, it may be necessary to reduce the total daily dosage.

Amoxicillin is contraindicated in penicillin hypersensitive patients.

Pregnancy and lactation : Animal studies with amoxicillin have shown no teratogenic effects. When antibiotic therapy is required during pregnancy, amoxicillin may be considered appropriate. During lactation, trace quantities of amoxicillin can be detected in breast milk.

Side-effects, as with other penicillins, are uncommon and mainly of a mild and transitory nature; they may include diarrhoea, indigestion, or occasionally rash, either urticarial or erythematous. An urticarial rash suggests penicillin hypersensitivity and the erythematous-type rash may arise if amoxicillin is administered to patients with glandular fever. In either case treatment should be discontinued. Pseudo-membranous colitis have been reported rarely.

Store in a cool and dry place, away from light. Keep out of reach of children.

D-Amoxy250 mg capsule : Box containing 10 strips of 10 capsules each. Each capsule contains amoxicillin trihydrate BP equivalent to 250 mg amoxicillin.
D-Amoxy500 mg capsule : Box containing 8 strips of 6 capsules each. Each capsule contains amoxicillin trihydrate BP equivalent to 500 mg amoxicillin.
D-Amoxysuspension : Dry powder in amber glass bottle for reconstitution into 100 ml suspension. After reconstitution, each 5 ml contains amoxicillin trihydrate BP equivalent to 125 mg amoxicillin.
D-AmoxyDS suspension : Dry powder in amber glass bottle for reconstitution into 100 ml suspension. After reconstitution each 5 ml contains amoxicillin trihydrate BP equivalent to 250 mg amoxicillin.
D-Amoxypaediatric drops : Dry powder in amber glass bottle for reconstitution into 15 ml suspension. After reconstitution each 1.25 ml contains amoxicillin trihydrate BPequivalent to 125 mg amoxicillin.